Dosing initiation and titration
Children four years and older with Lennox-Gastaut syndrome: Treatment should be initiated at a daily dose of approximately 10 mg/kg administered in two equally divided doses. The dose should be increased by approximately 10 mg/kg increments every other day to a target dose of 45 mg/kg/day or 3200 mg/day, whichever is less, administered in two equally divided doses. It is not known whether doses lower than the target doses are effective.
Adults with Lennox-Gastaut syndrome: Treatment should be initiated at a daily dose of 400-800 mg administered in two equally divided doses. The dose should be increased by 400-800 mg every other day until a maximum daily dose of 3200 mg, administered in two equally divided doses, is reached. It is not known whether doses lower than 3200 mg/day are effective.
Ask your healthcare provider about adding BANZEL to an existing treatment. As with all antiepileptic drugs, BANZEL should be withdrawn gradually, so be sure to talk to your healthcare professional before stopping or starting any medication.
Drug-Drug interactions - Tell your healthcare provider about all the medications your loved one takes, including prescription and non-prescription medications, vitamins, and herbal supplements.
Hormonal contraceptives – Using BANZEL at the same time as hormonal contraceptives may make the contraception less effective. Additional non-hormonal forms of contraception are recommended when taking BANZEL.
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